Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein

Thomas J. Lyons; Hongbin Liu; Joy J. Goto; Aram Nersissian; James A. Roe; Janet A. Graden; Carla Café; Lisa M. Ellerby; Dale E. Bredesen; Edith Butler Gralla; Joan Selverstone Valentine

doi:10.1073/pnas.93.22.12240

Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein

Thomas J. Lyons
, Hongbin Liu
, Joy J. Goto
, Aram Nersissian
, James A. Roe
, Janet A. Graden
, Carla Café
, Lisa M. Ellerby
, Dale E. Bredesen
, Edith Butler Gralla
, Joan Selverstone Valentine

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	12240-12244
Number of pages	5
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	93
Issue number	22
DOIs	https://doi.org/10.1073/pnas.93.22.12240
State	Published - Oct 29 1996

ASJC Scopus Subject Areas

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10.1073/pnas.93.22.12240

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Lyons, T. J., Liu, H., Goto, J. J., Nersissian, A., Roe, J. A., Graden, J. A., Café, C., Ellerby, L. M., Bredesen, D. E., Gralla, E. B., & Valentine, J. S. (1996). Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein. Proceedings of the National Academy of Sciences of the United States of America, 93(22), 12240-12244. https://doi.org/10.1073/pnas.93.22.12240

Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein. / Lyons, Thomas J.; Liu, Hongbin; Goto, Joy J. et al.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, No. 22, 29.10.1996, p. 12240-12244.

Research output: Contribution to journal › Article › peer-review

Lyons, TJ, Liu, H, Goto, JJ, Nersissian, A, Roe, JA, Graden, JA, Café, C, Ellerby, LM, Bredesen, DE, Gralla, EB & Valentine, JS 1996, 'Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein', Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 22, pp. 12240-12244. https://doi.org/10.1073/pnas.93.22.12240

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author = "Lyons, \{Thomas J.\} and Hongbin Liu and Goto, \{Joy J.\} and Aram Nersissian and Roe, \{James A.\} and Graden, \{Janet A.\} and Carla Caf{\'e} and Ellerby, \{Lisa M.\} and Bredesen, \{Dale E.\} and Gralla, \{Edith Butler\} and Valentine, \{Joan Selverstone\}",

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AU - Roe, James A.

AU - Graden, Janet A.

AU - Café, Carla

AU - Ellerby, Lisa M.

AU - Bredesen, Dale E.

AU - Gralla, Edith Butler

AU - Valentine, Joan Selverstone

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Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein

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