Teratogenic Effects of Serotonin Receptor 2B Disruption on the Migration and Cardiac Derivatives of the Cardiac Neural Crest

  • Brian K. Wells
  • , Gwyneth K. Garramone
  • , Amira Mahomed
  • , Max Ezin

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article numbere2506
Pages (from-to)e2506
JournalBirth Defects Research
Volume117
Issue number7
DOIs
StatePublished - Jul 2025

ASJC Scopus Subject Areas

  • Pediatrics, Perinatology, and Child Health
  • Embryology
  • Toxicology
  • Developmental Biology
  • Health, Toxicology and Mutagenesis

Keywords

  • 1-methylpsilocin
  • aorticopulmonary defects
  • cardiac neural crest cell migration
  • chicken embryo
  • interventricular septal defects
  • serotonin receptor 2B (5-HT2B)
  • serotonin receptor 2C (5-HT2C)
  • Signal Transduction
  • Cell Movement/drug effects
  • Serotonin 5-HT2 Receptor Agonists/pharmacology
  • Teratogens/toxicity
  • Teratogenesis/drug effects
  • Chick Embryo
  • Receptor, Serotonin, 5-HT2B/metabolism
  • Pregnancy
  • Animals
  • Serotonin 5-HT2 Receptor Antagonists/pharmacology
  • Heart Defects, Congenital
  • Serotonin/metabolism
  • Heart/embryology
  • Female
  • Receptor, Serotonin, 5-HT2C/metabolism
  • Neural Crest/metabolism

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